Characterization of group B streptococcal invasion in HEp-2 epithelial cells

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Characterization of group B streptococcal invasion of human chorion and amnion epithelial cells In vitro.

Group B streptococci (GBS) have been cultured from the chorioamnionic membrane of pregnant women, usually in association with chorioamnionitis and premature labor (K. A. Boggess, D. H. Watts, S. L. Hillier, M. A. Krohn, T. J. Benedetti, and D. A. Eschenbach, Obstet. Gynecol. 87:779-784, 1996). Colonization and infection of placental membranes can be a prelude to neonatal GBS infections even in ...

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Group B Streptococcal b-Hemolysin/Cytolysin Promotes Invasion of Human Lung Epithelial Cells and the Release of Interleukin-8

Pneumonia and lung injury are hallmarks of early-onset neonatal group B streptococcal (GBS) infections. Production of a b-hemolysin/cytolysin (b-h/c) encoded by the cylE gene is associated with GBS virulence in vivo. To elucidate the contribution of the b-h/c toxin to lung injury, the interactions of GBS wild-type strains and isogenic cylE mutants with A549 lung epithelial cells were examined. ...

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Group B Streptococcal Sepsis in a Newborn: a Case Report

Newborns’ bacterial infections due to group B Streptococcus (GBS) happen in two forms including early-onset disease or late-onset disease. In this paper, we report a case of early-onset GBS infection in a male infant. A 22-year-old primigravid woman delivers a term normal looking male infant. Nasal flaring, grunting, and poor feeding presented soon after birth. An empiric treatment wit...

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Group B streptococcal beta-hemolysin/cytolysin promotes invasion of human lung epithelial cells and the release of interleukin-8.

Pneumonia and lung injury are hallmarks of early-onset neonatal group B streptococcal (GBS) infections. Production of a beta-hemolysin/cytolysin (beta-h/c) encoded by the cylE gene is associated with GBS virulence in vivo. To elucidate the contribution of the beta-h/c toxin to lung injury, the interactions of GBS wild-type strains and isogenic cylE mutants with A549 lung epithelial cells were e...

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The Rate of HEP-2 Cellular Invasion of Salmonella Serogroups in Diarrhea Patients

Abstract Background and Objectives: gasterointertidis is one of the most common forms of Salmonellosis, which is a worldwide problem. The invasive characteristic of intestinal bacteria is one of their pathogenicity Mechanisms , which can be easily investigated by cell culture technique. In this study ,the invasive characteristic of some Salmonella serogroup were investigated by using HEP-2 ...

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ژورنال

عنوان ژورنال: FEMS Microbiology Letters

سال: 1997

ISSN: 0378-1097

DOI: 10.1016/s0378-1097(96)00506-x